Marc A. Holbert : rechercher sur Z-Library

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1

Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

Erin M. Bowers, Gai Yan, Chandrani Mukherjee, Andrew Orry, Ling Wang, Marc A. Holbert, Nicholas T. Crump, Catherine A. Hazzalin, Glen Liszczak, Hua Yuan, Cecilia Larocca, S. Adrian Saldanha, Ruben Aba

Journal:

Chemistry & Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2010

2

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

Tang, Yong, Holbert, Marc A, Wurtele, Hugo, Meeth, Katrina, Rocha, Walter, Gharib, Marlene, Jiang, Eva, Thibault, Pierre, Verrault, Alain, Cole, Philip A

Journal:

Nature Structural and Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 693 KB

english, 2008

3

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

Tang, Yong, Holbert, Marc A, Wurtele, Hugo, Meeth, Katrina, Rocha, Walter, Gharib, Marlene, Jiang, Eva, Thibault, Pierre, Verreault, Alain, Cole, Philip A

Journal:

Nature Structural and Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 92 KB

english, 2008

4

Structure and activity of enzymes that remove histone modifications

Marc A Holbert, Ronen Marmorstein

Journal:

Current Opinion in Structural Biology

Année:

2005

Langue:

english

Fichier:

PDF, 675 KB

english, 2005

5

Protein tyrosine kinase–substrate interactions

Ron Bose, Marc A Holbert, Kerry A Pickin, Philip A Cole

Journal:

Current Opinion in Structural Biology

Année:

2006

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2006

6

Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation

Yong Tang, Marc A. Holbert, Neda Delgoshaie, Hugo Wurtele, Benoît Guillemette, Katrina Meeth, Hua Yuan, Paul Drogaris, Eun-Hye Lee, Chantal Durette, Pierre Thibault, Alain Verreault, Philip A. Cole, R

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2011

7

De Novo Discovery of Serotonin N-Acetyltransferase Inhibitors

Szewczuk, Lawrence M., Saldanha, S. Adrian, Ganguly, Surajit, Bowers, Erin M., Javoroncov, Margarita, Karanam, Balasubramanyam, Culhane, Jeffrey C., Holbert, Marc A., Klein, David C., Abagyan, Ruben

Journal:

Journal of Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 408 KB

english, 2007

8

Acetylation of the p53 DNA-Binding Domain Regulates Apoptosis Induction

Stephen M. Sykes, Hestia S. Mellert, Marc A. Holbert, Keqin Li, Ronen Marmorstein, William S. Lane, Steven B. McMahon

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2006

9

Site-Specific Introduction of an Acetyl-Lysine Mimic into Peptides and Proteins by Cysteine Alkylation

Huang, Rong, Holbert, Marc A., Tarrant, Mary Katherine, Curtet, Sandrine, Colquhoun, David R., Dancy, Beverley M., Dancy, Blair C., Hwang, Yousang, Tang, Yong, Meeth, Katrina, Marmorstein, Ronen, Cole

Journal:

Journal of the American Chemical Society

Année:

2010

Langue:

english

Fichier:

PDF, 525 KB

english, 2010

10

Component co-expression and purification of recombinant human pyruvate dehydrogenase complex from baculovirus infected SF9 cells

Jiang, Yong, Wang, Juan, Zhang, Guofeng, Oza, Khyati, Myers, Linda, Holbert, Marc A., Sweitzer, Sharon

Journal:

Protein Expression and Purification

Année:

2014

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2014

11

An Fc Domain Protein–Small Molecule Conjugate as an Enhanced Immunomodulator

Chiang, Meng-Jung, Holbert, Marc A., Kalin, Jay H., Ahn, Young-Hoon, Giddens, John, Amin, Mohammed N., Taylor, Martin S., Collins, Samuel L., Chan-Li, Yee, Waickman, Adam, Hsiao, Po-Yuan, Bolduc, Davi

Journal:

Journal of the American Chemical Society

Année:

2014

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2014

12

“Nucleosome binding alters the substrate bonding environment of Histone H3 Lysine 36 Methyltransferase NSD2”

Poulin, Myles B., Schneck, Jessica L, Matico, Rosalie E., Hou, Wangfang, McDevitt, Patrick J., Holbert, Marc, Schramm, Vern L.

Journal:

Journal of the American Chemical Society

Année:

2016

Langue:

english

Fichier:

PDF, 451 KB

english, 2016

13

Development of a high-content imaging assay for screening compound aggregation

Jiang, Yong, Hoffman, Ann, Quinque, Geoffrey, Bonnette, William G., Szewczuk, Lawrence M., Holbert, Marc A., Gross, Jeffrey

Journal:

Analytical Biochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 942 KB

english, 2018

14

High-Throughput Cellular Thermal Shift Assays in Research and Drug Discovery

Henderson, Mark J., Holbert, Marc A., Simeonov, Anton, Kallal, Lorena A.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 275 KB

english, 2019

15

High-Throughput Cellular Thermal Shift Assays in Research and Drug Discovery

Henderson, Mark J., Holbert, Marc A., Simeonov, Anton, Kallal, Lorena A.

Journal:

Année:

2019

Fichier:

PDF, 275 KB

2019